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Latest Findings

External facilitation increases uptake of ActionADE

  • We tried out a helpful approach to assist in putting ActionADE into action in four VCH emergency departments.

  • A facilitator teamed up with local delivery teams to come up with plans to deal with challenges in making ActionADE work smoothly.

  • We put into practice eight activities. This included things like sharing stories from patients and holding educational meetings.

  • As a result, reporting of adverse drug events went up by 2.33 times.

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Unveiling differences in adverse drug event reporting systems

  • We compared adverse drug event reports in two systems: the Patient Safety Learning System – Adverse Drug Reactions (PSLS-ADR) and ActionADE, aiming to find out the differences in the volume and the types of events recorded.

  • We analyzed 3,248 ADE reports, revealing 11.6% in PSLS-ADR and 88.4% in ActionADE

  • ActionADE captured 4- to 6-fold more comparable events than PSLS-ADR during the study period.

  • Common culprit drugs:
    – PSLS-ADR: Iohexol, gadobutrol, and empagliflozin (46.2% of events).
    – ActionADE: Hydrochlorothiazide, apixaban, and ramipril (11.6% of events).

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Sharing Adverse Drug Event Insights for Safer Medication Practices

  • We analyzed 3,174 adverse drug event reports documented in ActionADE in four BC hospitals.

  • 34% of patients presenting to hospitals with adverse drug events attempt to refill the culprit drug.

  • Community pharmacists did not re-dispense the culprit drug in 33.0% of cases when presented with information about the prior ADE.

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