Published Research

We actively share our work on adverse drug event prevention and research work, not only in academic research articles, but also in presentations, background papers, and interviews with media outlets.

Research articles


Woo S., Cragg A., Wickham M.E., Villanyi D., Scheuermeyer F., Hau J.P., Hohl C.M. (2020) Preventable adverse drug events: Descriptive epidemiology. British Journal of Clinical Pharmacology. -Link-


Hohl C.M., Woo S.A., Cragg A., Wickham M.E., Ackerley C., Scheuermeyer F., Villanyi D. (2019) Repeat adverse drug events associated with outpatient medications: a descriptive analysis of 3 observational studies in British Columbia, Canada. CMAJ Open. -Link-


Woo S.A., Cragg A., Wickham M.E., Peddie D., Balka E., Scheuermeyer F., Villanyi D., Hohl C.M. (2018) Methods for evaluating adverse drug event preventability in emergency department patients. BMC Medical Research Methodology.  -Link-

Balka, E., Peddie, D., Small, S.S., Ackerley, C., Trimble, J., & Hohl, C.M. (2018). Barriers to scaling up participatory design interventions in health IT: A case study: Short Paper. In Proceedings of the Participatory Design Conference 2018 (PDC’ 18). Hasselt & Genk, Belgium, August 20-24, 2018. ACM, New York, NY, USA. -Link-

Peddie, D., Small, S.S., Badke, K., Bailey, C., Balka, E., Hohl, C.M. (2018). Adverse drug event reporting from clinical care: Mixed-methods analysis for a minimum required dataset. JMIR Med Inform. -Link-

Hohl C.M., Badke K., Zhao A., Wickham M.E., Woo S.A., Sivilotti M.L.A, Perry J.J. (2018) Prospective validation of clinical criteria to identify emergency department patients at high risk for adverse drug events. Academic Emergency Medicine. 25(9):1015-1026. -Link-

Hohl, C.M., Small, S.S., Peddie, D., Badke, K., Bailey, C., Balka, E. (2018). Why clinicians don’t report adverse drug events: A qualitative study. JMIR Public Health and Surveillance. -Link-


Hohl, C.M., Partovi, N., Ghement, I., Wickham, M.E., McGrail, K., Reddekopp, L.N., & Sobolev, B. (2017). Impact of early in-hospital medication review by clinical pharmacists on health services utilization. PLOS One. -Link-

Small, S.S., Peddie, D., Ackerley, C.A., Hohl, C.M., & Balka, E. (2017). Patient experiences with informational discontinuity of care: Bridging the gaps. Proceedings from The 7th International Conference on Current and Future Trends of Information and Communication Technologies in Healthcare (ICTH2017). Lund, Sweden: September 18-20, 2017. -Link-

Small, S.S., Peddie, D., Ackerley, C.A., Hohl, C.M., & Balka, E. (2017). Patient perceptions about data sharing and privacy: Insights from ActionADE. Proceedings from Context Sensitive Health Informatics 2017. Hong Kong: August 18-19, 2017. -Link-

Peddie D., Small S., Wickham M., Bailey C., Hohl C.M. and Balka E. (2017). Designing novel health ICTs to support work, not generate it: Five principles. Proceedings of Information Technology and Communications in Health 2017, Victoria, 2017. -Link-

Peddie D., Small S., Ackerley C., Bailey C., Wickham M., Hohl, C.M., Balka, E. (2017). Action ADE: Enabling Cross-setting Communication to Prevent Adverse Drug Events. Companion of the 2017 ACM Conference on Computer Supported Cooperative Work and Social Computing. -Link-

Stockton, K.R., Wickham, M.E., Lai, S., Badke, K., Dahri, K., Villanyi, D., Ho, V., & Hohl, C.M. (2017). Incidence of clinically relevant medication errors in the era of electronically prepopulated medication reconciliation forms: A retrospective chart review. CMAJ Open. -Link-


Chruscicki, A., Badke, K., Peddie, D., Small, S., Balka, E., & Hohl, C.M. (2016). Pilot-testing an adverse drug event reporting form prior to its implementation in an electronic health record. SpringerPlus. -Link-

Peddie, D., Small, S.S., Badke, K., Wickham. M.E., Bailey, C., Chruscicki, A., Ackerley, C., Balka, E., Hohl, C. M. (2016). Designing an Adverse Drug Event Reporting System to Prevent Unintentional Reexposures to Harmful Drugs: Study Protocol for a Multiple Methods Design. JMIR Research Protocols. -Link-

Hohl, C., Balka, E. & Ackerley, C. (2016). Technology to prevent adverse drug events. Quality Matters, 9(1), 32-27. -Link- 

Bailey, C., Peddie, D., Wickam, M. E., Badke, K., Small, S., Doyle-Waters, M. M., Balka, E. & Hohl, C. (2016). Adverse drug event reporting systems – A systematic review. British Journal of Clinical Pharmacology. -Link-


Hohl, C., Lexchin, J. R., & Balka, E. (2015). Can reporting of adverse drug reactions create safer systems while improving health data? CMAJ. -Link-

Hohl, C., McGrail K., & Sobolev, B.G. (2015). The Effect of Pharmacist-Led Medication Review in High-Risk Emergency Department Patients: Evaluation Protocol of a Quality Improvement Program. CMAJ Open, 3(1):E103-110. -Link-


Hohl, C., Karpov, A., Redekopp, L., & Staussberg, J. (2014). ICD-10 Codes Used to Identify Adverse Drug Events in Administrative Data: A Systematic Review. Journal of the American Medical Informatics Association, 21(3), 547-557.-Link-


Hohl, C., Garrison, S., Lang, E., Lexchin, J., Sobolev, B.G., Rowe, B. …Holland, R. (2013). The effect of early pharmacist-led medication review in acute care on health outcomes: a systematic review. PROSPERO. -Link-

Hohl, C., Kuramoto L, Rogula B, Yu E, & Sobolev B. (2013). Evaluating adverse drug event reporting in administrative data from emergency departments: a validation study. BMC Health Services Research, 13, 473. -Link-.

Bailey, C., Lander, B., Balka, E., & Hohl, C. (2013). A systematic review of adverse drug event reporting systems. PROSPERO. -Link-


Hohl, C., De Lemos, J., & Abu-Laban, R. (2012). Emergency Hospitalizations for Adverse Drug Events. New England Journal of Medicine, -Link-

Hohl, C., Yu, E.S., Hunte, G., Brubacher, J.R., Hosseini, F., Argent, C.,…Singer, J. (2012). Clinical Decision Rules to Improve the Detection of Adverse Drug Events in Emergency Department Patients. Academic Emergency Medicine. -Link-


Hohl, C. M., Nosyk, B., Kuramoto, L., Zed, P. J., Brubacher, J. R., Abu-Laban, R. B., . . . Sobolev, B. (2011). Outcomes of emergency department patients presenting with adverse drug events. Annals of Emergency Medicine,  -Link-


Hohl, C., Abu-Laban, R.B., Zed, P.J., Brubacher, J., Tsai, G., Kretz P,…Purssell, R. (2010). Patient-Reported Adverse Drug Related Events to Emergency Department Discharge Prescriptions. Canadian Journal of Emergency Medicine. -Link-

Hohl, C., Zed, P.J., Brubacher, J.R., Abu-Laban, R.B., Loewen, P.S., Purssell, R. (2010). Do Emergency Physicians Attribute Drug-Related Emergency Department Visits to Medication-Related Problems? Annals of Emergency Medicine-Link-


Hohl, C., Abu-Laban, R.B., Zed, P.J., Sobolev, B., Brubacher, J.R., Tsai, G., …Purssell, R. (2009). Adherence with Emergency Department Discharge Prescriptions. Canadian Journal of Emergency Medicine-Link-

2008 & Earlier

Zed, P. J., Abu-Laban, R. B., Balen, R. M., Loewen, P. S., Hohl, C. M., Brubacher, J. R., . . . Purssell, R. A. (2008). Incidence, severity and preventability of medication-related visits to the emergency department: A prospective study. Canadian Medical Association Journal-Link-

Hohl, C., Robitaille, C., Lord, V., Dankoff, J., Colacone, A., Pham, L., …Afilalo, M. (2005). Emergency Physician Recognition of Adverse Drug Related Events in Elderly Patients Presenting to an Emergency Department. Academic Emergency Medicine-Link-

Hohl, C. M., Dankoff, J., Colacone, A., & Afilalo, M. (2001). Polypharmacy, adverse drug-related events, and potential adverse drug interactions in elderly patients presenting to an emergency department. Annals of Emergency Medicine-Link-

Selected publications

Other relevant research & resources

Important research is being conducted around the world to better understand how adverse drug events happen, and how to prevent them.

For more information on adverse drug events and related topics, explore the resources posted on:

Research highlight: Data Impact Challenge for preventable adverse drug events

ImagineNation Challenges tasks Canadian researchers to seek answers to important questions about our health and health system.

A team of researchers from ICES Western tackled the 2016 question, “To what extent does re-prescribing and re-dispensing of culprit drugs contribute to the burden of adverse drug events presenting to Canadian hospitals?”

ICES Western’s winning entry is summarized in the infographic below (click to view a larger PDF). 32


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