In 2012, our team was funded to develop new adverse drug event reporting methods to address the shortcomings of existing systems.
As part of the initial research process, we:
- Conducted a systematic review of adverse drug event reporting systems globally, identifying 108 adverse drug event reporting systems containing 1782 unique data fields. In light of this variability, we suggested that developing a common standardized data set is likely to optimize adverse drug event data and drug safety surveillance.
- Held participatory design workshops engaging end-users – including physicians, pharmacists, and nurses from various healthcare settings – to share their needs and help co-design the Action ADE interface. We connected with over 180 frontline care providers in workshops to inform our design.
- Completed over 350 hours of workplace observation understand work practices associated with adverse drug event documentation and communication in various health care settings.
- Conducted pilot-testing of a paper-based version of the ActionADE application in emergency department settings.
- Pilot tested the ActionADE application in the emergency department and hospital wards of Vancouver General Hospital from June 2018
- ActionADE application is currently being used to support BC’s Patient Safety & Learning System at pilot hospital sites in the reporting of serious adverse drug reactions to Health Canada for Vanessa’s Law
Now, we are fully funded to refine, implement, and evaluate the ActionADE application are in British Columbia. This phase will include a qualitative evaluation, a randomized control trial, and an economic analysis.
Alongside the ActionADE project, we are also conducting other research projects on the factors causing preventable adverse drug events, the rates and nature of preventable adverse drug events, and clinical decision tools to screen for patients at high risk of adverse drug events.
Including Patient Insights
Patient Oriented Research
Within this approach, it is vital to also engage patients as partners and focus on patient-identified priorities with the goals of improving patient experiences, health outcomes and the health system.
By conducting patient-oriented research, we hope to:
- Develop and address relevant patient-oriented research questions about adverse drug events.
- Improve health literacy about adverse drug events.
- Promote patient participation in medication management decisions, and in identifying and preventing adverse drug events.
- Empower patients to participate in prioritizing the dissemination of research results to decision-makers.
More heads are better than one
Integrated Knowledge Translation
The ActionADE uses an integrated knowledge translation approach to research, meaning we involve knowledge-users throughout the research process to co-produce evidence that is relevant to their needs.
In integrated knowledge translation, researchers and research users work together to shape the research process by collaborating to determine the research questions, decide on the methodology, conduct data collection and tools development, interpret the findings, and help disseminate the research results. 26-29 The central assumption of integrated knowledge translation is that involving knowledge users as partners alongside researchers will lead to research that is more relevant and useful to the knowledge users. 27-30 It is meant to cross disciplinary boundaries through collaboration, and transform practice and policy. 31
We believe the most effective way to prevent adverse drug events is using integrated knowledge translation to tap into the rich knowledge of stakeholders, and involve them in the research, design, implementation, and evaluation of the ActionADE Application.